Cri du chat

Additional symptoms affecting different organ systems of the body can also occur.Most cases are thought arise from spontaneous (de novo) genetic errors very early in embryonic development.Some are also at risk for aspiration which can lead to pneumonias.In one study, only 50% of children with cri du chat syndrome were able to feed themselves with a spoon by 3.5 years of age.

Abnormal side-to-side curvature of the spine (scoliosis) is a frequent complication.

As affected infants age the face may lose its plumpness and become abnormally long and narrow.

Most affected infants also display some degree of psychomotor and intellectual disability.

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NORD gratefully acknowledges Scott Pentiuk MD, Assistant Professor of Pediatrics, Cincinnati Children's Hospital Medical Center, and Adam Mezoff, MD, Professor of Pediatrics, Cincinnati Children's Hospital Medical Center, for assistance in the preparation of this report.

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